What we know — and don’t know — about Russia’s ‘Sputnik V’ vaccine

While details about the research behind the vaccine are limited, here’s what we know so far.The vaccine was developed by the Moscow-based Gamaleya Institute, using funding from the Russian Direct Investment Fund (RDIF). The vaccine is named Sputnik V — a reference to the 1957 Soviet Union satellite.Scientists conducted months of human trials but are…


Scroll for Your Story

Search MORE Story

How to Choose Replacement Glass For WindowsIt can be difficult to decide what window replacement option to choose from the
The Ultimate Texas Sheet Cake My Ultimate Texas Sheet Cake recipe is everything a great cake should be: soft, moist,
DO NOT USE THEIR HOSTING List https://www.websiteplex.com/ WebsitePlex very rude in behavioral pattern - the poor resourced American hosting company
Yuddham Sharanam (4K) - नागा चैतन्य की सुपरहिट एक्शन हिंदी डब्ड मूवी | Naga Chaitanya & Lavanya The movie story
अजय देवगन ने अपनी सच्चाई घरवालों को बतायी अजय देवगन ने अपनी सच्चाई घरवालों को बतायी Movie:- Yeh Raaste Hain
WAKING UP Bean | Mr Bean Funny Clips | Mr Bean Official Mr Bean, late for his dental appointment, tries
ब्रह्मानंदम बता रहा है अल्लू अर्जुन को Rules काम करने के लिए ब्रह्मानंदम बता रहा है अल्लू अर्जुन को Rules
Use Your Imagination In Your Intimate enthusiasm We humans continually have some of the additional thoughts going upon in our
Still, the most good blue stake online acting websites wish pass a collection of line roulette and sap variants that

Explore S.

→ Story You’re Creating or Missing . . .

feel the openness

Your Story here :

185 people 👁️ing this randomly

While details about the research behind the vaccine are limited, here’s what we know so far.

The vaccine was developed by the Moscow-based Gamaleya Institute, using funding from the Russian Direct Investment Fund (RDIF). The vaccine is named Sputnik V — a reference to the 1957 Soviet Union satellite.

Scientists conducted months of human trials but are yet to publish data and did not begin the crucial Phase 3 stage, which usually precedes approval, before the announcement on Tuesday.

On Wednesday it was announced that a Phase 3 trial involving more than 2,000 people in Russia and several Middle Eastern and Latin American countries had begun. Typically this stage of trial involves testing on tens of thousands of people.

Dr. Scott Gottlieb, former commissioner of the US Food and Drug Administration (FDA), said Tuesday that the number of people the vaccine had been tested on so far was the equivalent of a Phase 1 trial, which typically involves a small group and studies the safety of the vaccine.

Is the Russian vaccine safe?

The short answer is that we don’t know. Russia has released no scientific data on its vaccine testing and CNN is unable to verify claims about its safety or effectiveness. But Russia says the vaccine has passed through Phase 1 and Phase 2 trials which were completed on August 1.

A Phase 1 study typically focuses on whether a vaccine is safe and whether it elicits an immune response in a small number of people.

“We do not have any information whatsoever on whether this is safe,” Keith Neal, Emeritus Professor of the Epidemiology of Infectious Diseases, University of Nottingham, told CNN.

Russia claims that volunteers in the Phase 1 and 2 trials felt well after taking the vaccine, and exhibited no unforeseen or unwanted side effects.

Neal said that researchers were unlikely to have detected any rare side effectslinked to the Gamaleya vaccine.

“You won’t know about side effects without [widespread] testing, if they’re rare. That’s the point of a Phase 3 study,” he said.

“I wouldn’t take it, certainly not outside of a clinical trial right now,” Gottlieb told CNN Tuesday.

Is the vaccine effective?

Without data and completed Phase 3 trials, Russia has not proven to the world Sputnik V works.

“I would think that it at least produces antibodies. What we don’t know is if it protects people against infection,” Neal told CNN.

Russia has said that its vaccine is an adenoviral vector one. Adenoviruses cause the common cold, but in Covid-19 vaccines they’re weakened and modified to deliver genetic material that codes for a protein from the novel coronavirus.

Russia, the US and the Covid-19 vaccine free-for-allRussia, the US and the Covid-19 vaccine free-for-all

The body then produces that protein and may produce an immune response against it but the method can cause problems.

Sputnik V’s makers say the vaccine induced a “strong antibody and cellular immune response,” in trial volunteers, according to the official website for the vaccine.

“Not a single participant of the current clinical trials got infected with Covid-19 after being administered with the vaccine,” the statement adds.

“It’s not clear how efficacious the Russian vaccine is going to be and whether or not people have some prior immunity to the adenovirus that they’re using to deliver the coronavirus gene sequence,” Gottlieb told CNN Tuesday.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, expressed similar concerns.

“I hope that the Russians have actually, definitively proven that the vaccine is safe and effective. I seriously doubt that they’ve done that,” Fauci told Deborah Roberts of ABC News for a National Geographic event to broadcast Thursday. A portion of the interview was posted by National Geographic on Tuesday.

How did Russia pull this off so quickly?

In April, Russia enacted a law which eliminated the need for a Phase 3 vaccine trial before approval.

Approval now means the coronavirus vaccine can be distributed even as Phase 3 tests get underway — though practically speaking, mass-manufactured doses aren’t expected to be ready for weeks.

“They’re not as far ahead as other vaccines,” Neal said, noting that Moderna and Oxford’s vaccines have already begun Phase 3 trials.

Critics say Russia’s haste is partly due to political pressure from the Kremlin, which is keen to portray the country as a global scientific force.

Russia is not alone when it comes to fast tracking — China approved an experimental coronavirus vaccine in June for members of its military.

And while its vaccine data from Phase 1 and 2 trials are yet to be published, US, UK and Canadian security officials warned in July that Russian cyber actors were targeting organizations involved in coronavirus vaccine development.

Who will get it first?

Russia’s Health Ministry has said the country’s frontline medical staff and teachers will be the first vaccinated.

The country plans to begin mass vaccination of citizens in October, Kirill Dmitriev, CEO of the RDIF told CNN on Tuesday.

“We will start massive vaccination of Russians in October. This vaccine will be available to other countries around November,” Dmitriev told CNN’s Anderson Cooper and Dr. Sanjay Gupta.

At the end of July officials denied reports that members of the country’s political and business elite — including Putin — had been given early access to the vaccine.

Russia plans to mass produce the vaccine by September 2020.

Which countries will take the vaccine? And which won’t?

A lot of countries appear keen to try Sputnik V. Dmitriev said at a Tuesday press conference that Russia had “received preliminary applications for over 1 billion doses of the vaccine from 20 countries.”

“Countries in Latin America, the Middle East and Asia have displayed the greatest interest in the vaccine, and we are about to finalize a number of contracts for the purchase of the vaccine,” he added.

Philippines President Rodrigo Duterte has publicly expressed his enthusiasm for the vaccine and claimed that he is willing to volunteer in further trials.

“I will volunteer to receive it in public. I will be the first to be experimented on,” Duterte said during his address to the Philippines late Monday broadcast by state-run RTVM.

As it stands, the Russian vaccine is unlikely to be meet approval regulations for European Union countries and in the US, will need the FDA’s approval.

“The US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have fast-track approval procedures for emergency humanitarian use and we need to see evidence that Russia is adopting an equally prudent approach,” said Duncan Matthews, Professor of IP Law at Queen Mary University of London, in a statement to the Science Media Center.

“The point is not to be first with a vaccine. The point is to have a vaccine that is safe and effective for the American people and the people of the world,” US Health and Human Services Secretary Alex Azar said on ABC Tuesday.


Users & FEED

Search users

Total number of users: 13543

offline 1 hour


Comments: 0Publics: 1
offline 2 hours


Comments: 0Publics: 1
offline 4 hours


Comments: 0Publics: 0
offline 4 hours


Comments: 0Publics: 1
offline 4 hours


Comments: 0Publics: 1

Subscribe Some New Users to See FEED

Login or register to view the latest publications and comments from users for which you have subscribed.

Publication author

offline 1 day

SFH Admin

SFH Admin
Comments: 0Publics: 12539Registration: 28-10-2019

Leave a Reply

Your email address will not be published.

Password generation